Research & Development in Biotechnology & Bioinformatics
The prime
objectives of R&D at ATG
1. To provide scientific support for small pharmaceutical industries for drug
development
2. To create innovative products for disease diagnostics
3. To build skilled human resource in biotechnology field
4. To introduce community control programs in health care research for
infectious diseases and genetic disorders
5. To carry contract research for academic and commercial establishments
Research Priorities
Virology
for infants and pediatric age group: Human Parvovirus B19, Cytomegalovirus, Hepatitis A virus and Rubella virus
Viral infections in pregnancy: CMV, HSV, Hepatitis E virus, Rubella and Parvovirus B19
Other economically important viruses: Shrimp hepatopancreatic parvovirus, Geminiviruses and plant viruses
Bioinformatics
solutions for animal and plant virology
Viral taxonomy studies
Viral genomics and proteomics
Genetics
and genomics
Sickle cell disease: Sickle cell anemia, Compound heterozygote: Diagnostics, therapeutics
Alpha and Beta Thalasesmia: Diagnostics kits, Therapeutics
Type 2 diabetes: TCF7L2 polymorphisms, other SNP studies
Bacteriology
Alkaliphiles: evolutionary studies, biotechnological applications
Thermophiles: evolutionary studies, biotechnological applications
Halophiles: evolutionary studies, biotechnological applications
Biotechnological applications in Bioremediation
Molecular
drug resistance:
Drug resistance in parasite: Drug resistance of Plasmodium falciparum towards antimalarials
Drug resistance in viruses: Drug resistance of human cytomegalovirus towards Gancyclovir
Collaborations with NGO and pharmaceutical companies
1. Research Project with pharmaceutical company
Collaboration with
Pathak pharmaceuticals, Nagpur
for finding newer
anti- sickling agents from
traditional herbal products (ongoing project) Status : In Progress
2. Research Projects Completed with NGO -
"RESEARCH" (Regional Society for Education and Research in Community Health), Pune
1.
Pilot field studies on sickle cell anemia Ballarpur taluka district
Chandrapur
2.
Comprehensive prevalence on sickle cell anemia in 16 villages from
Ballarpur taluka
district Chandrapur
Research projects
1. Molecular diagnosis of drug resistant human cytomegalovirus (proposed)
2. TCF7L2 polymorphism studies in type 2 diabetes cases in Indian population (proposed)
3. Haplotyping of human beta globin gene (proposed)
4. Sickle cell anemia pathogenesis studies in Indian tribes (current project)
5. Human parvovirus B19 prevalence studies in Indian population (proposed)
6. Peptide generation for human parvovirus B19 (proposed)
7. Pathogenesis studies on human Cytomegalovirus and human parvovirus B19 virus in pregnant women (proposed)
8. SNP studies in genetic disorders: Beta thalassemia, sickle cell anemia, type 2 diabetes (current project)
9. Antisickling properties of Ayurvedic and herbal products (current project)